To rule out that cable; run it without
Also on the cable there is a disclaimer (at lest for this cable)
https://www.newegg.com/asus-model-rs...82E16814997024
Disclaimer
This product is only compatible for devices that support the PCI-E 3.0 specification. If you use this product with a motherboard that supports PCI-E 4.0, please enter into BIOS option and select PCIE 3.0 before installation.
ALSO FYI Samsung 500 pro has a little slower read speed then 1 or 2tb
Good luck getting this worked out